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KMID : 1137820180390040147
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의공학회지
2018 Volume.39 No. 4 p.147 ~ p.152
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Study of Lipid Coated Polymeric Nanoparticles for Lung Metastasis
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Park Jun-Young
Park Sang-Hyo
Jo Ye-Rim
Jeong Min-Ji
Kim In-Woo
Kang Won-Jun
Key Jae-Hong
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Abstract
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Lung cancer and pulmonary metastasis are the leading cause of cancer mortality worldwide. Survival for patients with lung metastases is about 5%. Nanoparticles have been developed for the imaging and treatment of various cancers, including pulmonary malignancies. In this work, we report lipid coated polymeric nanoparticles (LPNs) with an average diameter of 154 nm. In vivo performance of LPNs was characterized using optical imaging system. We expect this nanoparticle can be used for finding lung cancer or lung metastasis. Eventually loading therapeutic drug with the nanoparticle will be utilized for cancer diagnosis and effective therapy at the same time.
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KEYWORD
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Lung cancer, Lung metastasis, Lipid coated polymeric nanoparticles, Imaging
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